PD-L1 Antikörper

Produktnummer ABIN7266180

Produktdetails anti-PD-L1 Antikörper

Target: PD-L1 (CD274 (PD-L1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PD-L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Inhibition Assay (InhA)

Verwendungszweck: PD-L1/CD274 Rabbit mAb

Kreuzreaktivität: Human

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Reinheit: ≥95 % purity by SDS-PAGE

Immunogen: Recombinant protein of human PD-L1/CD274.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Elisa,1:500 - 1:2000,WB,1:500 - 1:2000,FC,1:50 - 1:200,Inhibition,1 μg/ul

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.09 % sodium azide, 50 % glycerol, pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PD-L1

Target: PD-L1 (CD274 (PD-L1))

Andere Bezeichnung: PD-L1 (PD-L1 Produkte)

Synonyme: B7-H antikoerper, B7H1 antikoerper, PD-L1 antikoerper, PDCD1L1 antikoerper, PDCD1LG1 antikoerper, PDL1 antikoerper, A530045L16Rik antikoerper, B7h1 antikoerper, Pdcd1l1 antikoerper, Pdcd1lg1 antikoerper, Pdl1 antikoerper, RGD1566211 antikoerper, CD274 molecule antikoerper, CD274 antigen antikoerper, programmed cell death 1 ligand 2 antikoerper, CD274 antikoerper, Cd274 antikoerper, PDCD1LG2 antikoerper

Hintergrund: Programmed death-ligand 1 (PD-L1) is a 40 kDa type 1 transmembrane protein that suppresses immune system. PD-L1 is expressed in hematopoietic and non-hematopoietic cells including T cells and B cells and various types of tumor cells. PD-L1 binds to its receptor Programmed death 1 (PD1). During infection or inflammation, PD1-PD-L1 interaction is important for preventing autoimmunity. In tumor microenvironments, PD1-PD-L1 interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human cancers. In recent years, PD-L1 has become an important biomarker and immunotherapy target for many types of malignancies.,B7-H,B7H1,PDL1,PD-L1,PDCD1L1,PDCD1LG1,CD274,Immunology & Inflammation,CD markers,PD-L1

Molekulargewicht: 20kDa/33kDa

Gen-ID: 29126

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints