CD27 Antikörper

Produktnummer ABIN7266175

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch CD27 in WB und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD27 Antikörper (ABIN7266175)

Target: CD27 (CD27 Molecule (CD27))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-CD27 Antikörper

Verwendungszweck: CD27 Rabbit mAb

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human CD27

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CD27

Target: CD27 (CD27 Molecule (CD27))

Andere Bezeichnung: CD27

Hintergrund: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008],S152, S152. LPFS2, T14, TNFRSF7, Tp55,Apoptosis,Cancer,CDs,Cell Biology & Developmental Biology,Cell Intrinsic Innate Immunity Signaling Pathway,Cytokines,Cytokines_TNF,Hematopoietic Progenitors,Immunology & Inflammation,Stem Cells,Tumor immunology,CD27

Molekulargewicht: 55kDa

Gen-ID: 939

UniProt: P26842

Pathways: Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints