BLOC1S3
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
IHC,1:50 - 1:200,IF,1:50 - 1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
BLOC1S3
(Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))
Andere Bezeichnung
BLOC1S3
Hintergrund
This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.,BLOC1S3,BLOS3,HPS8,RP,Signal Transduction,BLOC1S3