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alpha 2 Macroglobulin Antikörper

Der Kaninchen Monoklonal Anti-alpha 2 Macroglobulin-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, alpha 2 Macroglobulin in Proben von Human zu detektieren.
Produktnummer ABIN7265558

Kurzübersicht für alpha 2 Macroglobulin Antikörper (ABIN7265558)

Target

Alle alpha 2 Macroglobulin (A2M) Antikörper anzeigen
alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reaktivität

  • 106
  • 25
  • 24
  • 6
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 112
  • 22
  • 19
  • 4
  • 3
  • 1
Kaninchen

Klonalität

  • 127
  • 32
Monoklonal

Konjugat

  • 94
  • 23
  • 13
  • 7
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser alpha 2 Macroglobulin Antikörper ist unkonjugiert

Applikation

  • 106
  • 64
  • 46
  • 46
  • 38
  • 12
  • 9
  • 8
  • 8
  • 7
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Verwendungszweck

    Alpha-2-Macroglobulin (A2M) Rabbit mAb

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Monoclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    A synthesized peptide derived from human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M))

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

    Andere Bezeichnung

    A2M

    Hintergrund

    The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016],A2MD, CPAMD5, FWP007, S863-7,Blood,Blood_Serum Proteins,Cardiovascular,Cell Biology & Developmental Biology,Ubiquitin,A2M

    Molekulargewicht

    163kDa

    Gen-ID

    2

    UniProt

    P01023

    Pathways

    Lipid Metabolism
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