Caspase 4 Antikörper (AA 91-105)

Produktnummer ABIN7232775

Dieses Anti-Caspase 4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Caspase 4 in WB, ELISA und IHC (p). Geeignet für Human.

Kurzübersicht für Caspase 4 Antikörper (AA 91-105) (ABIN7232775)

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Caspase 4 Antikörper

Bindungsspezifität: AA 91-105

Verwendungszweck: Anti-Caspase-13 Rabbit Polyclonal Antibody

Spezifität: This antibody recognizes human, mouse, and rat caspase-13 (43 kDa).

Kreuzreaktivität: Human, Maus, Ratte

Immunogen: Peptide corresponding to aa 91- 105 of human caspase-13 (accession no. O75601).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunoblotting: use at 1 μg/mL.
Immunohistochemistry: use at 10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications.
Positive control: Whole cell lysate from HL60 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Dilute in PBS or medium which is identical to that used in the assay system.

Konzentration: Lot specific

Buffer: PBS, pH 7.4

Lagerung: -20 °C

Informationen zur Lagerung: This antibody is stable for at least one (1) year at -20°C. Avoid multiple freeze-thaw cycles.

Details zu Caspase 4

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Andere Bezeichnung: CASP13

Hintergrund: Caspase-13,Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival.,Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. Caspase-13 or ERICE (Evolutionarily Related Interleukin-1 Converting Enzyme) was recently described. When activated by caspase-8, caspase-13 induces apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.,CASP-13, EC 3.4.22.-, Evolutionary related interleukin-1-beta-converting enzyme, ERICE [Cleaved into: Caspase-13 subunit 1, Caspase-13 subunit 2]

Gen-ID: 338039

NCBI Accession: NP_788811

UniProt: O75601

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity