Vimentin Antikörper (pSer56)
Kurzübersicht für Vimentin Antikörper (pSer56) (ABIN7224926)
Target
Alle Vimentin (VIM) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- pSer56
-
Verwendungszweck
- Rabbit Anti-Vimentin (phospho Ser56) Polyclonal Antibody
-
Spezifität
- Phospho-Vimentin (S56) Polyclonal Antibody detects endogenous levels of Vimentin protein only when phosphorylated at S56.
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Immunogen
- Synthesized peptide derived from human Vimentin Phospho-Ser56
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
Haltbarkeit
- 12 months
-
-
- Vimentin (VIM)
-
Andere Bezeichnung
- Vimentin
-
Hintergrund
- VIM, VimentinVIM (vimentin) encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by VIM is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in VIM causes a dominant, pulverulent cataract.
-
Molekulargewicht
- 54kD
-
Gen-ID
- 7431
-
UniProt
- P08670
-
Pathways
- Caspase Kaskade in der Apoptose
Target
-