UIMC1 Antikörper

Produktnummer ABIN7232032

Der Kaninchen Polyklonal anti-UIMC1 Antikörper wird verwendet zum Nachweis von UIMC1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für UIMC1 Antikörper (ABIN7232032)

Target: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UIMC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-UIMC1 Antikörper

Verwendungszweck: UIMC1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of UIMC1 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human UIMC1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu UIMC1

Target: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Andere Bezeichnung: UIMC1

Hintergrund: Rabbit Anti-UIMC1 Polyclonal Antibody,BRCA1-A complex subunit RAP80, Receptor-associated protein 80, Retinoid X receptor-interacting protein 110, Ubiquitin interaction motif-containing protein 1,UIMC1 (Ubiquitin Interaction Motif Containing 1) is a Protein Coding gene. Among its related pathways are DNA Damage and DNA Double Strand Break Response. UIMC1 encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.,UIMC1

Molekulargewicht: observerd band 79kDa

Gen-ID: 51720

UniProt: Q96RL1

Pathways: DNA Reparatur, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus