UFD1L Antikörper

Produktnummer ABIN7232030

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch UFD1L in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für UFD1L Antikörper (ABIN7232030)

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UFD1L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-UFD1L Antikörper

Verwendungszweck: UFD1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of UFD1 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human UFD1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu UFD1L

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Andere Bezeichnung: UFD1

Hintergrund: Rabbit Anti-UFD1 Polyclonal Antibody,Ubiquitin recognition factor in ER-associated degradation protein 1, Ubiquitin fusion degradation protein 1, UB fusion protein 1,UFD1 (Ubiquitin Recognition Factor In ER Associated Degradation 1) is a Protein Coding gene. Diseases associated with UFD1 include Velocardiofacial Syndrome and Inclusion Body Myopathy With Paget Disease Of Bone And Frontotemporal Dementia. Among its related pathways are Protein processing in endoplasmic reticulum and Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template. The protein encoded by UFD1 forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in UFD1 have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.,UFD1

Molekulargewicht: observerd band 33kDa

Gen-ID: 7353

UniProt: Q92890