TYK2 Antikörper

Produktnummer ABIN7217414

Dieser Anti-TYK2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von TYK2 in WB, ELISA, IF und IHC (p). Geeignet für Human, Maus und Affe.

Kurzübersicht für TYK2 Antikörper (ABIN7217414)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reaktivität: Human, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TYK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TYK2 Antikörper

Verwendungszweck: Tyk 2 Polyclonal Antibody

Spezifität: Tyk 2 Polyclonal Antibody detects endogenous levels of Tyk 2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Tyk 2 around the non-phosphorylation site of Y1054

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Andere Bezeichnung: Tyk 2

Hintergrund: Rabbit Anti-Tyk 2 Polyclonal Antibody,TYK2, Non-receptor tyrosine-protein kinase TYK2,TYK2 encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. Non-receptor tyrosine-protein kinase TYK2 associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.,Non-receptor tyrosine-protein kinase TYK2

Molekulargewicht: observerd band 134kDa

Gen-ID: 7297

UniProt: P29597

Pathways: JAK-STAT Signalweg, Hepatitis C