TSG101 Antikörper (AA 250-330)

Produktnummer ABIN7224820

Der Kaninchen Polyklonal Anti-TSG101 Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, TSG101 in Proben von Human, Maus, Ratte und Affe zu detektieren.

Kurzübersicht für TSG101 Antikörper (AA 250-330) (ABIN7224820)

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSG101 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TSG101 Antikörper

Bindungsspezifität: AA 250-330

Verwendungszweck: Tsg 101 Polyclonal Antibody

Spezifität: Tsg 101 Polyclonal Antibody detects endogenous levels of Tsg 101 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Tsg 101 at AA range: 250-330

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TSG101

Target: TSG101 (Tumor Susceptibility Gene 101 (TSG101))

Andere Bezeichnung: Tsg 101

Hintergrund: Rabbit Anti-Tsg 101 Polyclonal Antibody,TSG101, Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101,The protein encoded by TSG101 (tumor susceptibility 101) belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in TSG101 occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.,Tumor susceptibility gene 101 protein

Molekulargewicht: observerd band 44kDa

Gen-ID: 7251

UniProt: Q99816