Tropomyosin Antikörper (AA 101-150)

Produktnummer ABIN7231914

Der Kaninchen Polyklonal anti-Tropomyosin Antikörper wird verwendet zum Nachweis von Tropomyosin in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Tropomyosin Antikörper (AA 101-150) (ABIN7231914)

Target: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tropomyosin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Tropomyosin Antikörper

Bindungsspezifität: AA 101-150

Verwendungszweck: Rabbit Anti-Tropomyosin α Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of Tropomyosin α

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human Tropomyosin alpha protein at AA range: 101-150

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Tropomyosin

Target: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Andere Bezeichnung: Tropomyosin alpha

Hintergrund: Tropomyosin alpha-1 chain, Alpha-tropomyosin, Tropomyosin-1TPM1 (Tropomyosin 1) is a Protein Coding gene. Diseases associated with TPM1 include Cardiomyopathy, Hypertrophic, 3 and Cardiomyopathy, Dilated, 1E. Among its related pathways are Striated Muscle Contraction and Dilated cardiomyopathy (DCM). This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in TPM1 are associated with type 3 familial hypertrophic cardiomyopathy.

Molekulargewicht: 38kD

Gen-ID: 7168

UniProt: P09493

Pathways: Regulation of Actin Filament Polymerization