TTF1 Antikörper (N-Term)

Produktnummer ABIN7224706

Dieser Anti-TTF1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von TTF1 in WB und ELISA. Geeignet für Human, Ratte und Maus.

Kurzübersicht für TTF1 Antikörper (N-Term) (ABIN7224706)

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TTF1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TTF-1 Polyclonal Antibody

Spezifität: TTF-1 Polyclonal Antibody detects endogenous levels of TTF-1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human TTF-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TTF1

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Andere Bezeichnung: TTF-1

Hintergrund: Rabbit Anti-TTF-1 Polyclonal Antibody,NKX2-1, NKX2A, TITF1, TTF1, Homeobox protein Nkx-2.1, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1, TTF-1,NKX2-1 (NK2 homeobox 1) encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in NKX2-1 are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for NKX2-1. This gene shares the symbol/alias TTF1 with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.,Homeobox protein Nkx-2.1

Molekulargewicht: observerd band 38kDa

Gen-ID: 7080

UniProt: P43699

Pathways: Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour