NFE4 Antikörper (acLys43)
Kurzübersicht für NFE4 Antikörper (acLys43) (ABIN7212636)
Target
Alle NFE4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- acLys43
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Verwendungszweck
- Rabbit Anti-NF-E4 (Acetyl Lys43) Polyclonal Antibody
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Spezifität
- Acetyl-NF-E4 (K43) Polyclonal AntibodySynthesized peptide derived from the human NF-E4 around the acetylation site of K43.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from the human NF-E4 around the acetylation site of K43
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Haltbarkeit
- 12 months
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- NFE4 (Transcription Factor NF-E4 (NFE4))
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Andere Bezeichnung
- NF-E4
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Hintergrund
- NFE4, Transcription factor NF-E4The erythroid-specific protein encoded by NFE4, and the ubiquitous transcription factor CP2, form the stage selector protein(SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG(CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform(22 kDa) acts as an activator, the short isoform(14 kDa) has been shown to repress gamma-globin gene expression. NFE4 is located in an intron of the FBXL13 gene on the opposite strand.
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Molekulargewicht
- 19kD
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Gen-ID
- 58160
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UniProt
- Q86UQ8
Target
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