NFE4 Antikörper (AA 102-136)
Kurzübersicht für NFE4 Antikörper (AA 102-136) (ABIN6242127)
Target
Alle NFE4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 102-136
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This NFE4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 102-136 amino acids from the Central region of human NFE4.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- NFE4 (Transcription Factor NF-E4 (NFE4))
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Andere Bezeichnung
- NFE4
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Hintergrund
- Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
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Molekulargewicht
- 19019
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UniProt
- Q86UQ8
Target
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