TOP3A Antikörper (AA 350-430)

Produktnummer ABIN7226600

Der Kaninchen Polyklonal anti-TOP3A Antikörper wird verwendet zum Nachweis von TOP3A in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für TOP3A Antikörper (AA 350-430) (ABIN7226600)

Target: TOP3A (Topoisomerase (DNA) III alpha (TOP3A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOP3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TOP3A Antikörper

Bindungsspezifität: AA 350-430

Verwendungszweck: Rabbit Anti-Topo IIIα Polyclonal Antibody

Spezifität: Topo IIIα Polyclonal Antibody detects endogenous levels of Topo IIIα protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Topo IIIalpha at AA range: 350-430

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TOP3A

Target: TOP3A (Topoisomerase (DNA) III alpha (TOP3A))

Andere Bezeichnung: Topo IIIalpha

Hintergrund: TOP3A, TOP3, DNA topoisomerase 3-alpha, DNA topoisomerase III alphaTOP3A(topoisomerase(DNA) III alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 115kD

Gen-ID: 7156

UniProt: Q13472

Pathways: DNA Reparatur