TOP3A Antikörper (AA 350-430)

Produktnummer ABIN7226600

Der Kaninchen Polyklonal Anti-TOP3A Antikörper wurde für WB und ELISA validiert. Er ist geeignet, TOP3A in Proben von Human und Maus zu detektieren.

Kurzübersicht für TOP3A Antikörper (AA 350-430) (ABIN7226600)

Target: TOP3A (Topoisomerase (DNA) III alpha (TOP3A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOP3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TOP3A Antikörper

Bindungsspezifität: AA 350-430

Verwendungszweck: Topo IIIα Polyclonal Antibody

Spezifität: Topo IIIα Polyclonal Antibody detects endogenous levels of Topo IIIα protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Topo IIIalpha at AA range: 350-430

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TOP3A

Target: TOP3A (Topoisomerase (DNA) III alpha (TOP3A))

Andere Bezeichnung: Topo IIIalpha

Hintergrund: Rabbit Anti-Topo IIIα Polyclonal Antibody,TOP3A, TOP3, DNA topoisomerase 3-alpha, DNA topoisomerase III alpha,TOP3A(topoisomerase(DNA) III alpha) encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.,DNA topoisomerase 3-alpha

Molekulargewicht: observerd band 115kDa

Gen-ID: 7156

UniProt: Q13472

Pathways: DNA Reparatur