TINF2 Antikörper (AA 40-120)

Produktnummer ABIN7220998

Der Kaninchen Polyklonal Anti-TINF2 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, TINF2 in Proben von Human zu detektieren.

Kurzübersicht für TINF2 Antikörper (AA 40-120) (ABIN7220998)

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TINF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TINF2 Antikörper

Bindungsspezifität: AA 40-120

Verwendungszweck: TIN2 Polyclonal Antibody

Spezifität: TIN2 Polyclonal Antibody detects endogenous levels of TIN2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human TIN2 at AA range: 40-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TINF2

Target: TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))

Andere Bezeichnung: TIN2

Hintergrund: Rabbit Anti-TIN2 Polyclonal Antibody,TINF2, TIN2, TERF1-interacting nuclear factor 2, TRF1-interacting nuclear protein 2,TINF2 encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The TERF1 interacting nuclear factor 2 encoded by TINF2 is a critical part of shelterin, it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.,TERF1-interacting nuclear factor 2

Molekulargewicht: observerd band 53kDa

Gen-ID: 26277

UniProt: Q9BSI4

Pathways: Zellzyklus, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process