TRF2 Antikörper (AA 130-210)

Produktnummer ABIN7231756

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TRF2 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für TRF2 Antikörper (AA 130-210) (ABIN7231756)

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TRF2 Antikörper

Bindungsspezifität: AA 130-210

Verwendungszweck: Rabbit Anti-TERF2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of TERF2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human TERF2 protein at AA range: 130-210

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TRF2

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Andere Bezeichnung: TERF2

Hintergrund: Telomeric repeat-binding factor 2 , TTAGGG repeat-binding factor 2, Telomeric DNA-binding proteinTERF2 encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

Molekulargewicht: 55kD

Gen-ID: 7014

UniProt: Q15554

Pathways: Zellzyklus, Telomere Maintenance