SYN1 Antikörper (pSer62)

Produktnummer ABIN7224568

Der Kaninchen Polyklonal Anti-SYN1 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, SYN1 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für SYN1 Antikörper (pSer62) (ABIN7224568)

Target: SYN1 (Synapsin I (SYN1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SYN1 Antikörper

Bindungsspezifität: pSer62

Verwendungszweck: Synapsin I (phospho Ser62) Polyclonal Antibody

Spezifität: Phospho-Synapsin I (S62) Polyclonal Antibody detects endogenous levels of Synapsin I protein only when phosphorylated at S62.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Synapsin I Phospho-Ser62

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu SYN1

Target: SYN1 (Synapsin I (SYN1))

Andere Bezeichnung: Synapsin I

Hintergrund: Rabbit Anti-Synapsin I (phospho Ser62) Polyclonal Antibody,SYN1, Synapsin-1, Brain protein 4.1, Synapsin I,SYN1 (synapsin I) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in SYN1 may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.,Synapsin-1

Molekulargewicht: observerd band 80kDa

Gen-ID: 6853

UniProt: P17600