SMC1B Antikörper (AA 110-190)

Produktnummer ABIN7231408

Dieser Anti-SMC1B Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von SMC1B in WB und ELISA. Geeignet für Human.

Kurzübersicht für SMC1B Antikörper (AA 110-190) (ABIN7231408)

Target: SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SMC1B Antikörper

Bindungsspezifität: AA 110-190

Verwendungszweck: SMC1B Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of SMC1B protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SMC1B protein at AA range: 110-190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu SMC1B

Target: SMC1B (Structural Maintenance of Chromosomes 1B (SMC1B))

Andere Bezeichnung: SMC1B

Hintergrund: Rabbit Anti-SMC1B Polyclonal Antibody,Structural maintenance of chromosomes protein 1B, SMC protein 1B, SMC-1-beta, SMC-1B,SMC1B (Structural Maintenance Of Chromosomes 1B) is a Protein Coding gene. Among its related pathways are Meiosis and Oocyte meiosis. An important paralog of this gene is SMC1A. Meiosis-specific component of cohesin complex. Required for the maintenance of meiotic cohesion, but not, or only to a minor extent, for its establishment. Contributes to axial element (AE) formation and the organization of chromatin loops along the AE. Plays a key role in synapsis, recombination and chromosome movements. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity).,SMC1B

Molekulargewicht: observerd band 135kDa

Gen-ID: 27127

UniProt: Q8NDV3