Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Mammaglobin A in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.
SCGB2A2
Reaktivität: Human
WB, IHC
Wirt: Kaninchen
Monoclonal
unconjugated
Applikationshinweise
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
Mammaglobin A (SCGB2A2)
(Secretoglobin, Family 2A, Member 2 (SCGB2A2))
Andere Bezeichnung
Mammaglobin A
Hintergrund
SCGB2A2, MGB1, UGB2, Mammaglobin-A, Mammaglobin-1, Secretoglobin family 2A member 2Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement. Tissue specificity: mammary gland specific. Over-expressed in breast cancer.