ARHGEF7 Antikörper (AA 280-360)

Produktnummer ABIN7225698

Dieser Anti-ARHGEF7 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ARHGEF7 in WB, ELISA und IHC (p). Geeignet für Human, Ratte und Maus.

Kurzübersicht für ARHGEF7 Antikörper (AA 280-360) (ABIN7225698)

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ARHGEF7 Antikörper

Bindungsspezifität: AA 280-360

Verwendungszweck: PIXβ Polyclonal Antibody

Spezifität: PIXβ Polyclonal Antibody detects endogenous levels of PIXβ protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human PIXbeta at AA range: 280-360

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu ARHGEF7

Target: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Andere Bezeichnung: PIXbeta

Hintergrund: Rabbit Anti-PIXβ Polyclonal Antibody,ARHGEF7, COOL1, KIAA0142, P85SPR, PAK3BP, PIXB, Nbla10314, Rho guanine nucleotide exchange factor 7, Beta-Pix, COOL-1, PAK-interacting exchange factor beta, p85,ARHGEF7 (Rho guanine nucleotide exchange factor 7) encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for ARHGEF7.,Rho guanine nucleotide exchange factor 7

Molekulargewicht: observerd band 80kDa

Gen-ID: 8874

UniProt: Q14155

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation