REV1 Antikörper

Produktnummer ABIN7231002

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch REV1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für REV1 Antikörper (ABIN7231002)

Target: REV1 (REV1, Polymerase (DNA Directed) (REV1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REV1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-REV1 Antikörper

Verwendungszweck: Rabbit Anti-REV1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of REV1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human REV1 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu REV1

Target: REV1 (REV1, Polymerase (DNA Directed) (REV1))

Andere Bezeichnung: REV1

Hintergrund: DNA repair protein REV1, Alpha integrin-binding protein 80, AIBP80, Rev1-like terminal deoxycytidyl transferaseREV1 encodes REV1, DNA Directed Polymerase with similarity to the S. cerevisiae mutagenesis protein Rev1. The Rev1 proteins contain a BRCT domain, which is important in protein-protein interactions. A suggested role for the human Rev1-like protein is as a scaffold that recruits DNA polymerases involved in translesion synthesis (TLS) of damaged DNA.

Molekulargewicht: 137kD

Gen-ID: 51455

UniProt: Q9UBZ9

Pathways: DNA Reparatur, Regulation of Actin Filament Polymerization, Production of Molecular Mediator of Immune Response