RGS4 Antikörper (AA 80-160)

Produktnummer ABIN7231032

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch RGS4 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für RGS4 Antikörper (AA 80-160) (ABIN7231032)

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RGS4 Antikörper

Bindungsspezifität: AA 80-160

Verwendungszweck: RGS4 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RGS4 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RGS4 protein at AA range: 80-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu RGS4

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Andere Bezeichnung: RGS4

Hintergrund: Rabbit Anti-RGS4 Polyclonal Antibody,Regulator of G-protein signaling 4, RGP4, RGS4,RGS4 (Regulator Of G Protein Signaling 4) is a Protein Coding gene. Diseases associated with RGS4 include Schizophrenia 9 and Schizophrenia. Among its related pathways are Signaling by GPCR and ADP signalling through P2Y purinoceptor 12. Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for RGS4.,RGS4

Molekulargewicht: observerd band 22kDa

Gen-ID: 5999

UniProt: P49798

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling