RGS4 Antikörper (AA 1-188)

Produktnummer ABIN783994

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RGS4 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schaf und Schwein.

Kurzübersicht für RGS4 Antikörper (AA 1-188) (ABIN783994)

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Schaf, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RGS4 Antikörper

Bindungsspezifität: AA 1-188

Spezifität: Recognizes RGS4

Kreuzreaktivität (Details): Species reactivity (expected):Cow (97 %), Rat (97 %), Rabbit (96 %), Pig (96 %), Sheep (97 %)Species reactivity (tested):Human, Mouse.

Aufreinigung: Antigen-Affinity Chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 188 of Human RGS4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.43 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 20 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody undiluted (in aliquots) at -20 °C.

Details zu RGS4

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Andere Bezeichnung: RGS4

Hintergrund: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq]Synonyms: RGP4, Regulator of G-protein signaling 4

Gen-ID: 5999

NCBI Accession: NP_005604

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling