rala Antikörper (AA 170-250)

Produktnummer ABIN7230952

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch rala in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für rala Antikörper (AA 170-250) (ABIN7230952)

Target: rala (Ras-related Protein Ral-A (rala))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser rala Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-rala Antikörper

Bindungsspezifität: AA 170-250

Verwendungszweck: Rabbit Anti-RASL1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RASL1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RASL1 protein at AA range: 170-250

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu rala

Target: rala (Ras-related Protein Ral-A (rala))

Andere Bezeichnung: RASL1

Hintergrund: RasGAP-activating-like protein 1, RAS protein activator like 1, Ras GTPase-activating-like proteinThe protein encoded by RASAL1 (RAS Protein Activator Like 1) is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.

Molekulargewicht: 88kD

Gen-ID: 8437

UniProt: O95294

Pathways: Neurotrophin Signalübertragung, SARS-CoV-2 Protein Interaktom