RASIP1 Antikörper (AA 620-700)

Produktnummer ABIN7230920

Dieser Anti-RASIP1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von RASIP1 in WB und ELISA. Geeignet für Human.

Kurzübersicht für RASIP1 Antikörper (AA 620-700) (ABIN7230920)

Target: RASIP1 (Ras Interacting Protein 1 (RASIP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RASIP1 Antikörper

Bindungsspezifität: AA 620-700

Verwendungszweck: RAIN Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of RAIN protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RAIN protein at AA range: 620-700

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu RASIP1

Target: RASIP1 (Ras Interacting Protein 1 (RASIP1))

Andere Bezeichnung: RAIN

Hintergrund: Rabbit Anti-RAIN Polyclonal Antibody,Ras-interacting protein 1, Rain,Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.,RAIN

Molekulargewicht: observerd band 105kDa

Gen-ID: 54922

UniProt: Q5U651