RAD21 Antikörper (AA 490-570)

Produktnummer ABIN7223894

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RAD21 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für RAD21 Antikörper (AA 490-570) (ABIN7223894)

Target: RAD21 (RAD21 Homolog (RAD21))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RAD21 Antikörper

Bindungsspezifität: AA 490-570

Verwendungszweck: Rabbit Anti-Rad21 Polyclonal Antibody

Spezifität: Rad21 Polyclonal Antibody detects endogenous levels of Rad21 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Rad21 at AA range: 490-570

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:5000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Andere Bezeichnung: Rad21

Hintergrund: RAD21, HR21, KIAA0078, NXP1, Double-strand-break repair protein rad21 homolog, hHR21, Nuclear matrix protein 1, NXP-1, SCC1 homologThe protein encoded by RAD21 (RAD21 cohesin complex component) is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.

Molekulargewicht: 120-130kD

Gen-ID: 5885

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity