Der Kaninchen Polyklonal anti-RAB3GAP2 Antikörper wird verwendet zum Nachweis von RAB3GAP2 in Proben von Human, Maus, Ratte und Affe. Er wurde validiert für ELISA, WB, IHC und IF.
RAB3GAP2
Reaktivität: Human
ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
RAB3GAP2
(RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2))
Andere Bezeichnung
Rab 3 GAP p150
Hintergrund
RAB3GAP2, KIAA0839, Rab3 GTPase-activating protein non-catalytic subunit, RGAP-iso, Rab3 GTPase-activating protein 150 kDa subunit, Rab3-GAP p150, Rab3-GAP150, Rab3-GAP regulatory subunitRAB3 GTPase activating non-catalytic protein subunit 2 encoded by RAB3GAP2 belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. RAB3 GTPase activating non-catalytic protein subunit 2 forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. RAB3GAP2 has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in RAB3GAP2 are associated with Martsolf syndrome.