PNKP Antikörper (AA 50-130)

Produktnummer ABIN7230720

Der Kaninchen Polyklonal anti-PNKP Antikörper (ABIN7230720) detektiert spezifisch PNKP in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für PNKP Antikörper (AA 50-130) (ABIN7230720)

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNKP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PNKP Antikörper

Bindungsspezifität: AA 50-130

Verwendungszweck: Rabbit Anti-PNKP Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PNKP protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PNKP protein at AA range: 50-130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PNKP

Target: PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))

Andere Bezeichnung: PNKP

Hintergrund: Bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase, Polynucleotide 3'-phosphatase, 2'(3')-polynucleotidase, Polynucleotide 5'-hydroxyl-kinasePNKP (Polynucleotide Kinase 3'-Phosphatase) is a Protein Coding gene. Diseases associated with PNKP includeAtaxia-Oculomotor Apraxia 4andMicrocephaly, Seizures, And Developmental Delay. Among its related pathways areDNA DamageandDNA damage_NHEJ mechanisms of DSBs repair.

Molekulargewicht: 57kD

Gen-ID: 11284

UniProt: Q96T60

Pathways: DNA Reparatur, Nucleotide Phosphorylation