PKD2 Antikörper (pSer876)

Produktnummer ABIN7213172

Der Kaninchen Polyklonal Anti-PKD2 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, PKD2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PKD2 Antikörper (pSer876) (ABIN7213172)

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PKD2 Antikörper

Bindungsspezifität: pSer876

Verwendungszweck: PKD2 (phospho Ser876) Polyclonal Antibody

Spezifität: Phospho-PKD2 (S876) Polyclonal Antibody detects endogenous levels of PKD2 protein only when phosphorylated at S876.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human PKD2 Phospho-Ser876

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PKD2

Target: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Andere Bezeichnung: PKD2

Hintergrund: Rabbit Anti-PKD2 (phospho Ser876) Polyclonal Antibody,PRKD2, PKD2, HSPC187, Serine/threonine-protein kinase D2, nPKC-D2,Protein kinase D2 encoded by PRKD2 belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. Protein kinase D2 can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.,serine threonine-protein kinase D2

Molekulargewicht: observerd band 96kDa

Gen-ID: 25865

UniProt: Q9BZL6

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity