PVRL4 Antikörper (AA 290-370)

Produktnummer ABIN7225202

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch PVRL4 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PVRL4 Antikörper (AA 290-370) (ABIN7225202)

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PVRL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PVRL4 Antikörper

Bindungsspezifität: AA 290-370

Verwendungszweck: Nectin 4 Polyclonal Antibody

Spezifität: Nectin 4 Polyclonal Antibody detects endogenous levels of Nectin 4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Nectin 4 at AA range: 290-370

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PVRL4

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Andere Bezeichnung: Nectin 4

Hintergrund: Rabbit Anti-Nectin 4 Polyclonal Antibody,PVRL4, LNIR, PRR4, Poliovirus receptor-related protein 4, Ig superfamily receptor LNIR, Nectin-4,NECTIN4 (nectin cell adhesion molecule 4) encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in NECTIN4 are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.,Poliovirus receptor-related protein 4

Molekulargewicht: observerd band 55kDa

Gen-ID: 81607

UniProt: Q96NY8

Pathways: Cell-Cell Junction Organization