PDGFRA Antikörper
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- Target Alle PDGFRA Antikörper anzeigen
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PDGFRA Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- Verwendungszweck
- PDGFRα Mouse Monoclonal Antibody (7A3)
- Spezifität
- PDGFRα protein detects endogenous levels of PDGFRA.
- Aufreinigung
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen
- Immunogen
- Synthetic Peptide of PDGFRalpha at AA range of 1010-1090
- Klon
- 7A3
- Isotyp
- IgG1
- Top Product
- Discover our top product PDGFRA Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:200).
- Kommentare
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Primary Antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Target
- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
- Andere Bezeichnung
- PDGFRalpha (PDGFRA Produkte)
- Synonyme
- AI115593 antikoerper, CD140a antikoerper, Pdgfr-2 antikoerper, APDGFR antikoerper, PDGFACE antikoerper, CD140A antikoerper, PDGFR-2 antikoerper, PDGFR2 antikoerper, RHEPDGFRA antikoerper, PDGFR antikoerper, PDGFR-A antikoerper, platelet derived growth factor receptor alpha antikoerper, platelet derived growth factor receptor, alpha polypeptide antikoerper, platelet-derived growth factor receptor, alpha polypeptide L homeolog antikoerper, platelet-derived growth factor receptor, alpha polypeptide antikoerper, PDGFRA antikoerper, Pdgfra antikoerper, pdgfra.L antikoerper
- Hintergrund
- Mouse Anti-PDGFRα Mouse Monoclonal Antibody (7A3),PDGFRA,PDGFRA (platelet derived growth factor receptor alpha) encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that PDGFRA plays a role in organ development, wound healing, and tumor progression. Mutations in PDGFRA have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.,PDGFRA
- Molekulargewicht
- observerd band 180kDa
- Gen-ID
- 5156
- UniProt
- P16234
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling
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