PDE5A Antikörper
Kurzübersicht für PDE5A Antikörper (ABIN7230560)
Target
Alle PDE5A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- PDE5A Polyclonal Antibody
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Spezifität
- The antibody detects endogenous levels of PDE5A protein
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human PDE5A protein
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
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Andere Bezeichnung
- PDE5A
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Hintergrund
- Rabbit Anti-PDE5A Polyclonal Antibody,cGMP-specific 3',5'-cyclic phosphodiesterase, cGMP-binding cGMP-specific phosphodiesterase, CGB-PDE,PDE5A (Phosphodiesterase 5A) is a Protein Coding gene. Diseases associated with PDE5A include Priapism and Nonarteritic Anterior Ischemic Optic Neuropathy. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Platelet homeostasis. PDE5A encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of PDE5A results in three transcript variants encoding distinct isoforms.,PDE5A
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Molekulargewicht
- observerd band 96kDa
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Gen-ID
- 8654
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UniProt
- O76074
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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