PDE3A Antikörper (AA 250-330)

Produktnummer ABIN7230556

Der Kaninchen Polyklonal anti-PDE3A Antikörper wird verwendet zum Nachweis von PDE3A in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für PDE3A Antikörper (AA 250-330) (ABIN7230556)

Target: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PDE3A Antikörper

Bindungsspezifität: AA 250-330

Verwendungszweck: Rabbit Anti-PDE3A Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PDE3A protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PDE3A protein at AA range: 250-330

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PDE3A

Target: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Andere Bezeichnung: PDE3A

Hintergrund: CGMP-inhibited 3',5'-cyclic phosphodiesterase A, Cyclic GMP-inhibited phosphodiesterase A, CGI-PDE APDE3A encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDE3A.

Molekulargewicht: 125kD

Gen-ID: 5139

UniProt: Q14432

Pathways: cAMP Metabolic Process