PER1 Antikörper (AA 1110-1190)

Produktnummer ABIN7230586

Der Kaninchen Polyklonal anti-PER1 Antikörper wird verwendet zum Nachweis von PER1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für PER1 Antikörper (AA 1110-1190) (ABIN7230586)

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PER1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PER1 Antikörper

Bindungsspezifität: AA 1110-1190

Verwendungszweck: Rabbit Anti-PER1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PER1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PER1 protein at AA range: 1110-1190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu PER1

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Andere Bezeichnung: PER1

Hintergrund: Period circadian protein homolog 1, hPER1, Circadian clock protein PERIOD 1, Circadian pacemaker protein RiguiPER1 is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER1 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER1 may increase the risk of getting certain cancers. Alternative splicing has been observed in PER1, however, these variants have not been fully described.

Molekulargewicht: 141kD

Gen-ID: 5187

UniProt: O15534

Pathways: Photoperiodism