PCM1 Antikörper (AA 140-220)

Produktnummer ABIN7230526

Dieser Anti-PCM1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von PCM1 in WB und ELISA. Geeignet für Human und Maus.

Kurzübersicht für PCM1 Antikörper (AA 140-220) (ABIN7230526)

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PCM1 Antikörper

Bindungsspezifität: AA 140-220

Verwendungszweck: PCM1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of PCM1 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PCM1 protein at AA range: 140-220

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu PCM1

Target: PCM1 (Pericentriolar Material 1 (PCM1))

Andere Bezeichnung: PCM1

Hintergrund: Rabbit Anti-PCM1 Polyclonal Antibody,Pericentriolar material 1 protein, PCM-1, hPCM-1,PCM1 (Pericentriolar Material 1) is a Protein Coding gene. Diseases associated with PCM1 include Differentiated Thyroid Carcinoma and Atypical Chronic Myeloid Leukemia. Among its related pathways are DNA Damage and Regulation of PLK1 Activity at G2/M Transition. The protein encoded by PCM1 is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for PCM1.,PCM1

Molekulargewicht: observerd band 222kDa

Gen-ID: 5108

UniProt: Q15154

Pathways: Stem Cell Maintenance, M Phase, Maintenance of Protein Location