Phospholipase D2 Antikörper (pTyr169)

Produktnummer ABIN7223198

Der Kaninchen Polyklonal anti-Phospholipase D2 Antikörper wird verwendet zum Nachweis von Phospholipase D2 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für Phospholipase D2 Antikörper (pTyr169) (ABIN7223198)

Target: Phospholipase D2 (PLD2)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase D2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Phospholipase D2 Antikörper

Bindungsspezifität: pTyr169

Verwendungszweck: Rabbit Anti-PC-PLD2 (phospho Tyr169) Polyclonal Antibody

Spezifität: Phospho-PC-PLD2 (Y169) Polyclonal Antibody detects endogenous levels of PC-PLD2 protein only when phosphorylated at Y169.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PC-PLD2 Phospho-Tyr169

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Phospholipase D2

Target: Phospholipase D2 (PLD2)

Andere Bezeichnung: PC-PLD2

Hintergrund: PLD2, Phospholipase D2, PLD 2, hPLD2, Choline phosphatase 2, PLD1C, Phosphatidylcholine-hydrolyzing phospholipase D2The protein encoded by PLD2 (phospholipase D2) catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for PLD2.

Molekulargewicht: 95kD

Gen-ID: 5338

UniProt: O14939

Pathways: RTK Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling