Neuregulin 1 Antikörper (AA 1-80)

Produktnummer ABIN7221488

Der Kaninchen Polyklonal Anti-Neuregulin 1 Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, Neuregulin 1 in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für Neuregulin 1 Antikörper (AA 1-80) (ABIN7221488)

Target: Neuregulin 1 (NRG1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuregulin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-Neuregulin 1 Antikörper

Bindungsspezifität: AA 1-80

Verwendungszweck: Neuregulin-1 SMDF Polyclonal Antibody

Spezifität: Neuregulin-1 SMDF Polyclonal Antibody detects endogenous levels of Neuregulin-1 SMDF protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Neuregulin-1 SMDF at AA range: 1-80

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Neuregulin 1

Target: Neuregulin 1 (NRG1)

Andere Bezeichnung: Neuregulin-1 SMDF

Hintergrund: Rabbit Anti-Neuregulin-1 SMDF Polyclonal Antibody,Pro-neuregulin-1 membrane-bound isoform, Pro-NRG1, NRG1, GGF, HGL, HRGA, NDF, SMDF,The neuregulin 1 encoded by NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).,Pro-neuregulin-1 membrane-bound isoform

Molekulargewicht: observerd band 44kDa

Gen-ID: 3084

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation