NDE1 Antikörper (AA 270-350)

Produktnummer ABIN7229926

Der Kaninchen Polyklonal anti-NDE1 Antikörper (ABIN7229926) detektiert spezifisch NDE1 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für NDE1 Antikörper (AA 270-350) (ABIN7229926)

Target: NDE1

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NDE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-NDE1 Antikörper

Bindungsspezifität: AA 270-350

Verwendungszweck: Rabbit Anti-NDE1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of NDE1 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human NDE1 protein at AA range: 270-350

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu NDE1

Target: NDE1

Andere Bezeichnung: NDE1

Hintergrund: Nuclear distribution protein nudE homolog 1, NudENDE1 (NudE Neurodevelopment Protein 1) encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic.

Molekulargewicht: 38kD

Gen-ID: 54820

UniProt: Q9NXR1