MLH3 Antikörper (AA 490-570)

Produktnummer ABIN7221088

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch MLH3 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MLH3 Antikörper (AA 490-570) (ABIN7221088)

Target: MLH3 (MutL Homolog 3 (MLH3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLH3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MLH3 Antikörper

Bindungsspezifität: AA 490-570

Verwendungszweck: MLH3 Polyclonal Antibody

Spezifität: MLH3 Polyclonal Antibody detects endogenous levels of MLH3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human MLH3 at AA range: 490-570

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MLH3

Target: MLH3 (MutL Homolog 3 (MLH3))

Andere Bezeichnung: MLH3

Hintergrund: Rabbit Anti-MLH3 Polyclonal Antibody,MLH3, DNA mismatch repair protein Mlh3, MutL protein homolog 3,MLH3 is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The mutL homolog 3 encoded by MLH3 functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.,DNA mismatch repair protein Mlh3

Molekulargewicht: observerd band 164kDa

Gen-ID: 27030

UniProt: Q9UHC1

Pathways: Chromatin Binding