MAP3K14 Antikörper (AA 90-170)

Produktnummer ABIN7229494

Der Kaninchen Polyklonal Anti-MAP3K14 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, MAP3K14 in Proben von Human zu detektieren.

Kurzübersicht für MAP3K14 Antikörper (AA 90-170) (ABIN7229494)

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAP3K14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MAP3K14 Antikörper

Bindungsspezifität: AA 90-170

Verwendungszweck: M3K14 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of M3K14 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human M3K14 protein at AA range: 90-170

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MAP3K14

Target: MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14 (MAP3K14))

Andere Bezeichnung: M3K14

Hintergrund: Rabbit Anti-M3K14 Polyclonal Antibody,Mitogen-activated protein kinase kinase kinase 14, NF-kappa-beta-inducing kinase, HsNIK, Serine/threonine-protein kinase NIK,MAP3K14 (Mitogen-Activated Protein Kinase Kinase Kinase 14) encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. MAP3K14 is a Protein Coding gene. Diseases associated with MAP3K14 include Nik Deficiency. Among its related pathways are 4-1BB Pathway and RANK Signaling in Osteoclasts.,M3K14

Molekulargewicht: observerd band 104kDa

Gen-ID: 9020

UniProt: Q99558

Pathways: NF-kappaB Signalweg, T-Zell Rezeptor Signalweg