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MEK1/2 Antikörper (pSer222, pSer226)

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch MEK1/2 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7223614

Kurzübersicht für MEK1/2 Antikörper (pSer222, pSer226) (ABIN7223614)

Target

MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))

Reaktivität

  • 83
  • 78
  • 78
  • 10
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 83
  • 1
Kaninchen

Klonalität

  • 65
  • 19
Polyklonal

Konjugat

  • 20
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Dieser MEK1/2 Antikörper ist unkonjugiert

Applikation

  • 71
  • 27
  • 27
  • 19
  • 14
  • 12
  • 11
  • 10
  • 9
  • 6
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 37
    • 21
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer222, pSer226

    Verwendungszweck

    MEK-1/2 (phospho Ser222/226) Polyclonal Antibody

    Spezifität

    Phospho-MEK-1/2 (S222/226) Polyclonal Antibody detects endogenous levels of MEK-1/2 protein only when phosphorylated at S222/226.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    Immunogen

    Synthesized peptide derived from human MEK-1/2 Phospho-Ser222/226

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

    Kommentare

    Primary Antibody

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • Target

    MEK1/2 (MAP2K1/2) (Mitogen-Activated Protein Kinase Kinase 1/2 (MAP2K1/2))

    Andere Bezeichnung

    MEK-1/2

    Hintergrund

    Rabbit Anti-MEK-1/2 (phospho Ser222/226) Polyclonal Antibody,MAP2K1, MEK1, PRKMK1, Dual specificity mitogen-activated protein kinase kinase 1, MAP kinase kinase 1, MAPKK 1, MKK1, ERK activator kinase 1, MAPK/ERK kinase 1, MEK 1, MAP2K2, MEK2, MKK2, PRKMK2, Dual specificity mitogen-activated protein k,The protein encoded by MAP2K1 (mitogen-activated protein kinase kinase 1) is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.,Dual specificity mitogen-activated protein kinase kinase 1

    Molekulargewicht

    observerd band 44kDa

    Gen-ID

    5604, 5605
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