MAPK15 Antikörper (pThr175)

Produktnummer ABIN7220514

Dieser Anti-MAPK15 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MAPK15 in WB, ELISA und IHC (p). Geeignet für Human und Maus.

Kurzübersicht für MAPK15 Antikörper (pThr175) (ABIN7220514)

Target: MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MAPK15 Antikörper

Bindungsspezifität: pThr175

Verwendungszweck: ERK 8 (phospho Thr175/Y177) Polyclonal Antibody

Spezifität: Phospho-ERK 8 (T175/Y177) Polyclonal Antibody detects endogenous levels of ERK 8 protein only when phosphorylated at T175/Y177.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human ERK 8 Phospho-Thr175/Y177

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MAPK15

Target: MAPK15 (Mitogen-Activated Protein Kinase 15 (MAPK15))

Andere Bezeichnung: ERK 8

Hintergrund: Rabbit Anti-ERK 8 (phospho Thr175/Y177) Polyclonal Antibody,MAPK15, ERK7, ERK8, Mitogen-activated protein kinase 15, MAP kinase 15, MAPK 15, Extracellular signal-regulated kinase 7, ERK-7, Extracellular signal-regulated kinase 8, ERK-8,The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.,Mitogen-activated protein kinase 15

Molekulargewicht: observerd band 60kDa

Gen-ID: 225689

UniProt: Q8TD08