MCPH1 Antikörper (AA 60-140)

Produktnummer ABIN7225086

Der Kaninchen Polyklonal anti-MCPH1 Antikörper wird verwendet zum Nachweis von MCPH1 in Proben von Human und Maus. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für MCPH1 Antikörper (AA 60-140) (ABIN7225086)

Target: MCPH1 (Microcephalin 1 (MCPH1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCPH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MCPH1 Antikörper

Bindungsspezifität: AA 60-140

Verwendungszweck: Microcephalin Polyclonal Antibody

Spezifität: Microcephalin Polyclonal Antibody detects endogenous levels of Microcephalin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Microcephalin at AA range: 60-140

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MCPH1

Target: MCPH1 (Microcephalin 1 (MCPH1))

Andere Bezeichnung: Microcephalin

Hintergrund: Rabbit Anti-Microcephalin Polyclonal Antibody,MCPH1, Microcephalin,MCPH1 (microcephalin 1) encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in MCPH1 have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.,Microcephalin

Molekulargewicht: observerd band 93kDa

Gen-ID: 79648

UniProt: Q8NEM0

Pathways: Stem Cell Maintenance