MMP17 Antikörper (Cleaved-Gln129)

Produktnummer ABIN7212492

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch MMP17 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MMP17 Antikörper (Cleaved-Gln129) (ABIN7212492)

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MMP17 Antikörper

Bindungsspezifität: AA 80-160, Cleaved-Gln129

Verwendungszweck: Cleaved-MMP-17 (Q129) Polyclonal Antibody

Spezifität: Cleaved-MMP-17 (Q129) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-17 protein resulting from cleavage adjacent to Q129.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human MMP-17 at AA range: 80-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MMP17

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Andere Bezeichnung: MMP-17

Hintergrund: Rabbit Anti-Cleaved-MMP-17 (Q129) Polyclonal Antibody,MMP17, MT4MMP, Matrix metalloproteinase-17, MMP-17, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP,MMP17 encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. Matrix metallopeptidase 17 is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of matrix metallopeptidase 17 protein has been observed in osteoarthritis and multiple human cancers.,Matrix metalloproteinase-17

Molekulargewicht: observerd band 53kDa

Gen-ID: 4326

UniProt: Q9ULZ9