MMP17 Antikörper (AA 391-420)

Produktnummer ABIN390141

Der Kaninchen Polyklonal anti-MMP17 Antikörper (Klon RB2033-2034) (ABIN390141) detektiert spezifisch MMP17 in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MMP17 Antikörper (AA 391-420) (ABIN390141)

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB2033-2034

Produktdetails anti-MMP17 Antikörper

Bindungsspezifität: AA 391-420

Homologie: M

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MMP17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-420 amino acids from the Central region of human MMP17.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MMP17

Target: MMP17 (Matrix Metallopeptidase 17 (Membrane-inserted) (MMP17))

Andere Bezeichnung: MMP17

Hintergrund: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP17 is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMPs in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage.

Molekulargewicht: 66653

Gen-ID: 4326

NCBI Accession: NP_057239

UniProt: Q9ULZ9