MRGPRX1 Antikörper (AA 240-320)

Produktnummer ABIN7220926

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch MRGPRX1 in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MRGPRX1 Antikörper (AA 240-320) (ABIN7220926)

Target: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGPRX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-MRGPRX1 Antikörper

Bindungsspezifität: AA 240-320

Verwendungszweck: MRGX1 Polyclonal Antibody

Spezifität: MRGX1 Polyclonal Antibody detects endogenous levels of MRGX1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human MRGX1 at AA range: 240-320

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MRGPRX1

Target: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Andere Bezeichnung: MRGX1

Hintergrund: Rabbit Anti-MRGX1 Polyclonal Antibody,MRGPRX1, MRGX1, SNSR3, SNSR4, Mas-related G-protein coupled receptor member X1, Sensory neuron-specific G-protein coupled receptor 3/4,MRGPRX1 (MAS Related GPR Family Member X1) is a Protein Coding gene. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is MRGPRX4. rphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) (PubMed: 26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.,Mas-related G-protein coupled receptor member X1

Molekulargewicht: observerd band 36kDa

Gen-ID: 259249

UniProt: Q96LB2