MRGPRX1 Antikörper (AA 271-320)

Produktnummer ABIN1535777

Der Kaninchen Polyklonal anti-MRGPRX1 Antikörper (ABIN1535777) detektiert spezifisch MRGPRX1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte und Maus.

Kurzübersicht für MRGPRX1 Antikörper (AA 271-320) (ABIN1535777)

Target: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRGPRX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MRGPRX1 Antikörper

Bindungsspezifität: AA 271-320

Verwendungszweck: MRGX1 Antibody

Spezifität: MRGX1 Polyclonal Antibody detects endogenous levels of MRGX1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000,IHC 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu MRGPRX1

Target: MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

Andere Bezeichnung: MRGX1

Hintergrund:

Synonyms: MRGPRX1, MRGX1, SNSR3, SNSR4, Mas-related G-protein coupled receptor member X1, Sensory neuron-specific G-protein coupled receptor 3/4

Background: function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,

Gene Name: MRGPRX1

Protein Name: Mas-related G-protein coupled receptor member X1

Molekulargewicht: 36 kDa

Gen-ID: 259249

OMIM: 607227

UniProt: Q96LB2