MASP2 Antikörper (AA 200-280)

Produktnummer ABIN7219136

Der Kaninchen Polyklonal anti-MASP2 Antikörper (ABIN7219136) detektiert spezifisch MASP2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MASP2 Antikörper (AA 200-280) (ABIN7219136)

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MASP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MASP2 Antikörper

Bindungsspezifität: AA 200-280

Verwendungszweck: MASP-2 Polyclonal Antibody

Spezifität: MASP-2 Polyclonal Antibody detects endogenous levels of MASP-2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human MASP-2 at AA range: 200-280

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu MASP2

Target: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Andere Bezeichnung: MASP-2

Hintergrund: Rabbit Anti-MASP-2 Polyclonal Antibody,MASP2, Mannan-binding lectin serine protease 2, MBL-associated serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2,MASP2 encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,Mannan-binding lectin serine protease 2

Molekulargewicht: observerd band 75kDa

Gen-ID: 10747

UniProt: O00187

Pathways: Komplementsystem